Single-center study with limited generalizability
The study was conducted in one critical care unit of a single private hospital in South Africa. This means the developed clinical pathway and the findings supporting its components are highly specific to that institution's context, resources, and patient population, making them not broadly applicable to other healthcare settings or regions.
Lack of pathway evaluation
The research focused solely on the *development* of the clinical pathway. It did not include any implementation or evaluation phase to assess the pathway's actual effectiveness in improving patient outcomes, reducing complications, or achieving cost-effectiveness in practice. The paper recommends future implementation and evaluation, indicating this as a significant gap in the current study.
Qualitative and contextual design
While appropriate for the exploratory aim, the qualitative, contextual, and descriptive design means the findings are based on expert opinions and literature review within a specific setting, rather than new empirical evidence from randomized trials or observational studies on patient outcomes. This limits the strength of evidence for the pathway's efficacy.
Small participant group for pathway development
The pathway components were identified and refined based on consensus from relatively small groups of multidisciplinary team members (15 in Phase 1, 20 in Phase 3). While typical for qualitative methods, this represents a limited range of perspectives for a tool intended to guide complex clinical practice.